Hieronder vind je quotes van allerlei karakters door de seizoenen heen.

- Dean tegen Sam (Seizoen 1, episode 1)

"So, fake US Marshall, fake credit cards. You got anything that's real?"
"My boobs"

-Gesprek tussen een agent en Dean (seizoen 1, episode 1)

- Dean tegen Sam (Seizoen 1, episode 1)

"You know... when you were a kid, I'd come home from a hunt. And after what I'd seen I'd be...I'd be wrecked. And you... you'd come up to me and you, you'd put your hand on my shoulder and you'd look me in they eye and, you'd say 'Its okay, dad.' Dean, I'm sorry."
"You shouldn't have had to say that to me. I-I should've been saying that to you. You know, I put- I put too much on your shoulders. I made you grow up too fast. You took care of Sammy, you took care of me. You did that. And you didn't complain, not once. I just want you to know that I am so proud of you."
"This really you talking?"
"Yeah. Yeah, it's really me."
"Why you saying this stuff?"
"I want you to watch out for Sammy, okay?"
"Yeah dad, you know I will. You're scaring me"

-Gesprek tussen Dean en John (seizoen 2, episode 1)

-Dean tegen Sam (Seizoen 10, episode 3)

"You know, when we were little, you couldn't have been more than five, you'd just started asking questions. How come we didn't have a mom; why do we always have to move around; where'd Dad go.. when he'd take off for days at a time. I remember I begged you, quit askin' Sammy, man, you don't wanna know. I just wanted you to be a kid. Just for a little while longer. I always tried to protect you, keep you safe. Dad didn't even have to tell me. This was always my responsibility, you know. It's like, I had one job. I had one job. And I screwed it up. I blew it. And for that I'm sorry. I guess that's what I do. I let down the people I love. I let Dad down, and now I guess I'm just supposed to let you down too. How can I? How am I supposed to live with that? What am I supposed to do? Sammy... God... What am I supposed to do? [screams] What am I supposed to do?"
-Dean tegen een dode Sam (seizoen 2, episode 22)

-Dean tegen zichzelf (Seizoen 3, episode 10)

"Maybe you could fight the mark for years. Maybe centuries, like Cain did. But you cannot fight it forever. And when you finally turn, and you will turn, Sam, and everyone you know, everyone you love, they could be long dead. Everyone except me. I’m the one who will have to watch you murder the world. So if there’s even a small chance that we can save you, I won’t let you walk out of this room."
Castiel tegen Dean (seizoen 10, episode 22)

-Gabriel op een video tape (seizoen 5, episode 19)

"I got a year to live, Sam. I'd like to make the most of it. So what do you say we kill some evil sons of bitches and we raise a little hell, huh?"
-Dean tegen Sam(seizoen 3, episode 1)

-Castiel tegen Dean (Seizoen 4, episode 1)

"It wasn't four months, you know."
"It was four months up here, but down there... I don't know. Time's different. It was more like 40 years.
"Oh, my God."
"They, uh... They sliced and carved and tore me in ways that you... until there was nothing left. And then, suddenly... I would be whole again... Like magic... Just so they could start in all over. And Alastair... At the end of every day... every one... He would come over. And he would make me an offer. To take me off the rack... If I put souls on...if I started the torture. And every day, I told him to stick it where the sun shines. For 30 years, I told him. But then I couldn't do it anymore, Sammy. I couldn't. And I got off that rack. God help me, I got right off it, and I started ripping them apart. I lost count of how many souls. The... the things that I did to them."
"Dean... Dean, look, you held out for 30 years. That's longer than anyone would have.
"How I feel... This... inside me... I wish I couldn't feel anything, Sammy I wish I couldn't feel a damn thing."
-Gesprek tussen Sam en Dean(seizoen 4, episode 10)

-Lucifer tegen Sam (Seizoen 7, episode 15)

"Adam doesn't have to be cursed."
"He's a Winchester. He's already cursed.
-Gesprek tussen Sam en Dean(seizoen 4, episode 19)

-Castiel tegen Dean (Seizoen 5, episode 18)

"You're Michael's weapon. Or rather his...receptacle."
"I'm a vessel?"
"You're the vessel. Michael's vessel."
"How? Why- why me?"
"Because you're chosen! It's a great honor, Dean."
"Oh, yeah. Yeah, life as an angel condom. That's real fun. I think I'll pass, thanks."

-Gesprek tussen Dean en Zachariah (Seizoen 5, episode 1)

- Dean tegen Sam (Seizoen 2, episode 4)

"You finally had what you wanted Dean."
"I wanted my brother! Alive!"
"You wanted a family. You have for a long time. Maybe the whole time. I know you. You only gave it up because of the way we lived. You had something. You were building something. Had I shown up Dean, you would've just run off."
-Gesprek tussen Sam en Dean (Seizoen 6, episode 1 )

- Dean tegen Sam (Seizoen 9, episode 23)

"Drop the attitude, Dean. Quit turning everything into a punchline. And you know something else? Stop trying to act like you're not afraid."
"I'm not!"
"You're lying. And you may as well drop it cause I can see right through you."
"You got no idea what you're talking about."
"Yeah, I do. You're scared Dean. You're scared because your year is running out and you're still going to hell, and you're freaked."
"And how do you know that?
"Because I know you!
"Yeah, because I've been following you around my entire life! I mean, I've been looking up to you since I was four, Dean. Studying you, trying to be just like my big brother. So yeah, I know you. Better that anyone else in the entire world. And this... is exactly how you act when you're terrified. And I mean, I can't blame you. It's just..." "What?" "It's just I wish you would drop the show and be my brother again. Cause... just cause."
-Gesprek tussen Sam en Dean(seizoen 3, episode 7)